Physician profile
John C Isaac
NPI 1295799005
$1,779,317.07
in general payments reported to CMS, 2019-2025
60 companies · $214K in 2025
The $214K reported for 2025 was more than what 99% of Interventional Cardiology providers received nationally (typical 2025 total: $1,092).
Payments by year
General payments by program year, as reported to CMS.
General payments by year: 2019: $435K · 2020: $233K · 2021: $273K · 2022: $283K · 2023: $140K · 2024: $200K · 2025: $214K.
What the payments were for
Nature of payment as categorized by the reporting companies: meals, consulting, travel, and so on.
Compensation For Services Other Than Consulting, Including Serving As Faculty Or As A Speaker At A Venue Other Than A Continuing Education Program: $429K · Travel and Lodging: $65K · Consulting Fee: $31K · Food and Beverage: $30K · Education: $20.22.
View as a table
| Payment type | Amount (2023-2025) |
|---|---|
| Compensation For Services Other Than Consulting, Including Serving As Faculty Or As A Speaker At A Venue Other Than A Continuing Education Program | $428,883.89 |
| Travel and Lodging | $64,554.84 |
| Consulting Fee | $31,407.00 |
| Food and Beverage | $29,510.52 |
| Education | $20.22 |
Payment-type detail covers 2023-2025; earlier years are included in totals but not broken out here.
Who reported paying
General payments only, as reported to CMS. Product names cover 2023-2025.
| Company | General payments | Years | Top products |
|---|---|---|---|
| Esperion Therapeutics, INC. | $355,721.14 | 2020-2025 | Nexletol, Nexlizet |
| Amgen INC. | $318,808.67 | 2019-2025 | Repatha, Repatha |
| Astrazeneca Pharmaceuticals Lp | $215,189.18 | 2019-2025 | Brilinta, Airsupra, Farxiga |
| Boehringer Ingelheim Pharmaceuticals, INC. | $127,834.60 | 2019-2025 | Jardiance |
| E.R. Squibb & Sons, L.L.C. | $125,497.04 | 2019-2025 | Camzyos, Eliquis |
| Sanofi-Aventis U.S. LLC | $118,008.69 | 2019-2024 | |
| Amarin Pharma, INC. | $87,213.49 | 2019-2023 | |
| Janssen Pharmaceuticals, INC | $85,233.07 | 2019-2024 | Xarelto |
| Lilly USA, LLC | $78,502.38 | 2019-2025 | Jardiance |
| Regeneron Healthcare Solutions, INC. | $58,363.77 | 2019-2025 | Evkeeza, Praluent |
| Kiniksa Pharmaceuticals International, Plc | $48,426.65 | 2024 | Arcalyst |
| Kiniksa Pharmaceuticals, Ltd. | $27,336.26 | 2021-2023 | Arcalyst |
| Novartis Pharmaceuticals Corporation | $26,955.16 | 2019-2025 | |
| Heartflow, INC. | $19,999.43 | 2019-2025 | |
| Impulse Dynamics (USA) INC. | $16,345.15 | 2021-2025 | Optimizer, Optimizer |
Show all 60 companies
| Company | General payments | Years | Top products |
|---|---|---|---|
| Althera Pharmaceuticals LLC | $13,751.02 | 2021-2022 | |
| Boston Scientific Corporation | $13,446.57 | 2019-2025 | Watchman Access System, Watchman Flx, Bodyguardian |
| Pfizer INC. | $12,251.53 | 2019-2025 | |
| Novo Nordisk INC | $10,684.27 | 2020-2025 | Ozempic, Rybelsus, Wegovy |
| Abbott Laboratories | $8,550.15 | 2019-2025 | Xience Xpedition, Optis, Cardiomems |
| Medicure Pharma INC. | $5,034.81 | 2021-2025 | Zypitamag |
| Medtronic, INC. | $1,105.88 | 2021-2025 | Selectsecure, Cobalt Dr Mri Surescan, Onyx Frontier |
| Merck Sharp & Dohme LLC | $667.81 | 2021-2025 | Verquvo, Capvaxive |
| Abiomed | $591.54 | 2019 | |
| Medtronic Vascular, INC. | $502.20 | 2019-2020 | |
| Alnylam Pharmaceuticals INC. | $287.22 | 2024-2025 | Amvuttra |
| Actelion Pharmaceuticals US, INC. | $286.87 | 2019-2025 | Opsumit, Uptravi |
| Bayer Healthcare Pharmaceuticals INC. | $262.12 | 2023-2025 | |
| Watermark Medical, INC. | $223.90 | 2020 | |
| Astellas Pharma US INC | $197.93 | 2019-2021 | |
| Arbor Pharmaceuticals, INC. | $190.51 | 2019-2021 | |
| Btg International INC. | $170.11 | 2024 | |
| Biotronik INC. | $165.35 | 2019-2020 | |
| Lexicon Pharmaceuticals, INC. | $145.63 | 2023-2024 | Inpefa |
| Elutia, INC. | $124.15 | 2019-2023 | |
| Irhythm Technologies, INC. | $120.40 | 2020-2024 | Zio Xt Patch, Zio Monitor |
| Acacia Pharma INC | $117.42 | 2021 | |
| Cardiva Medical, INC. | $110.60 | 2023-2025 | Cardiva Vascade 6/7f Vcs, Cardiva Vascade Mvp Xl Vvcs 10-12f, Cardiva Vascade Mvp Vvcs 6-12f |
| Bard Peripheral Vascular, INC. | $108.71 | 2020 | |
| Zoll Services LLC (A/K/A Zoll Lifecor Corp) | $101.64 | 2019-2025 | Lifevest |
| Inspire Medical Systems, INC. | $89.68 | 2023-2025 | Inspire |
| Kowa Pharmaceuticals America, INC. | $57.55 | 2019-2023 | Livalo |
| Scpharmaceuticals INC. | $50.71 | 2024-2025 | |
| Glaxosmithkline, LLC. | $46.14 | 2025 | Shingrix, Arexvy |
| Preventice Services, LLC | $42.27 | 2019-2020 | |
| G Medical Diagnostic Services, INC. | $41.69 | 2019 | |
| Altathera Pharmaceuticals LLC | $40.88 | 2023-2024 | Sotalol Hydrochloride |
| Azurity Pharmaceuticals, INC. | $36.58 | 2025 | Edarbi |
| Smith+Nephew, INC. | $32.18 | 2019 | |
| Avinger INC. | $31.78 | 2020 | |
| Chiesi USA, INC. | $28.11 | 2019-2020 | |
| Tactile Systems Technology INC | $27.73 | 2019-2023 | Flexitouch Plus, Entre Plus |
| Lundbeck LLC | $24.71 | 2020 | |
| Cvrx, INC. | $24.44 | 2022 | |
| Agepha Pharma Fz LLC | $20.68 | 2024 | Lodoco |
| Kestra Medical Technology Services, INC. | $19.22 | 2025 | Assure Wcd |
| Edwards Lifesciences Corporation | $18.16 | 2022 | |
| Ethicon US, LLC | $17.94 | 2019 | |
| Vivaquant INC, Dba Rhythm Express | $17.40 | 2021 | |
| Regeneron Pharmaceuticals, INC. | $16.20 | 2019 |
Drugs and devices associated with these payments
CMS records which products a payment was associated with, not how the money was allocated. Association is not allocation: one payment can be associated with several products, and a product listing does not mean the payment was made because of that product. Product detail covers 2023-2025.
If you want to bring it up
Most clinicians are glad to talk about this. A respectful way in:
- "I saw John Isaac listed in the CMS Open Payments database. Can you tell me about your work with those companies?"
- "Is there a generic or alternative to this medication, and would it work as well for me?"
- "What made you choose this particular treatment for my situation?"
These are normal questions. A good clinician will welcome them.
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Source: CMS Open Payments, program years 2019-2025, as reported to CMS by drug and device makers (published June 30, 2026). Drug and device detail covers 2023-2025.